This chamber provides valuable information and resources for area businesses and the greater community. The Greater Bluffton Chamber of Commerce is the only chamber chartered in Bluffton, S.C. Representing Lowcountry businesses in both incorporated and unincorporated areas, the chamber takes pride in being an organization that is “bridging the gap between the bridges.” The Greater Bluffton Chamber is the one and only “grassroots” chamber in southern Beaufort County.